【摘 要】
：
In this study, a novel reversed stationary phase based on dithiourea derivative modified silica (DT-Sil) was prepared and characterized, by infrared spectra and elemental analysis.Compared with the tr
【机 构】
：
Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics,
【出 处】
：
第2届大连国际色谱学术报告会、第37届国际高效液相色谱及相关技术会议、第18届全国色谱学术报告会
论文部分内容阅读
In this study, a novel reversed stationary phase based on dithiourea derivative modified silica (DT-Sil) was prepared and characterized, by infrared spectra and elemental analysis.Compared with the traditional C18 stationary phase, the new stationary phase has a more polar molecule structure, and the separation mechanism appears to involve multi-interaction including π-π, hydrophobic and hydrogen-bonding interactions.Using this stationary phase, aniline compounds, phenol compounds, polycyclic aromatic hydrocarbons, organophosphorus pesticide mixture and natural product mixtures were successfully separated respectively in reversed phase chromatography mode.Furthermore, the repeatability and stability of the DT-Sil stationary phase were also investigated.The results indicated that the novel reversed stationary phase, which possessed symmetric peak shape, high separation efficiency and good separation selectivity in RP-HPLC, was a good complement to the C 18 stationary phase.
其他文献
A lipid type molecular gel system was assembled on carrier particles to use as stationary phase for the separation bioactive-and shape-constrained isomers of tocopherols,-carotene, and polycyclic arom
The most commonly used measure for the performance of a chromatographic separation is plate counts.This value mainly depends on the particle size, column length and the packing quality of the column.H
Amnesic shellfish poisoning (ASP) is a well-known human food-borne intoxication caused by the consumption of contaminated shellfish.Domoic acid is the key chemical responsible for ASP1.HPLC is often t
The increasing demand for the analysis of polar compounds in biological and environmental samples promotes the development of hydrophilic-interaction chromatography (HILIC), which has better separatio
Packed bed stationary phase design has reached a point where transcolumn bed heterogeneities become a limiting factor to separation efficiency.Still, slurry packing a column is considered an art rathe
The most important innovation in the field of ordered mesoporous silicas (OMSs) is undoubtedly the use of bridged silsesquioxane molecules as precursors for the synthesis of periodic mesoporous organo
Laboratory samples of commercially available first-generation Chromolith columns are compared to their successor, the second-generation Chromolith columns.Plate height curve analysis allowed to determ
Poly(N-isopropylacylamide) (PNIPAAm), a typical temperature-responsive polymer, exhibits a reversible hydrophilic-hydrophobic change in water at its lower critical solution temperature (LCST) of 32℃,
Hydrophilic interaction liquid chromatography (HILIC) is an alternative method to reversed-phase liquid chromatography (RP-LC) for the separation of polar compounds.Hydrophilic stationary phase as the
Modern (U)HPLC columns with plate heights as low as 3-4 μm generate plate numbers on the order of 25 000-30 000 plates / 10 cm.For a 2.1x50 mm columns the peak variance is ca.5 μl2 (k =2).The separati