MFN2基因调控肺腺癌细胞增殖与侵袭作用

来源 :第十二届中青年呼吸学者论坛 | 被引量 : 0次 | 上传用户：beehall

【摘要】

：

目的:线粒体融合基因-2 (mitofusin-2,Mfn2,又名增殖抑制基因,hyperplasia suppressor gene,HSG)编码的蛋白具有促进线粒体融合作用.该基因最早从自发性高血压大鼠和正常血压大鼠的血管平滑肌细胞中通过差异显示克隆获得,前期研究发现MFN2是高血压的致病基因,近年来有报道提示其与多种肿瘤相关.然而,MFN2在肺腺癌发生发展中的机制尚不明确,本研究拟通过细胞水

【作者】

：

楼煜清李榕张岩巍刘洁琳张伟张雪艳钟华姜丽岩温绍君韩宝惠

【机构】

：

上海交通大学附属胸科医院首都医科大学附属北京安贞医院

【出处】

：

第十二届中青年呼吸学者论坛

【发表日期】

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2015年11期

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MFN2基因调控肺腺癌细胞增殖与侵袭作用

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