【摘 要】
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基于原发性黑色素瘤的Breslow深度,前哨淋巴结活检被认为是皮肤黑色素瘤的分期标准,而且是最重要的预后因素之一。但是当淋巴结内良性痣细胞与转移性黑色素瘤细胞相似时,对标
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基于原发性黑色素瘤的Breslow深度,前哨淋巴结活检被认为是皮肤黑色素瘤的分期标准,而且是最重要的预后因素之一。但是当淋巴结内良性痣细胞与转移性黑色素瘤细胞相似时,对标本的组织学分析就很困难。胰岛素样生长因子Ⅱ信使RNA结合蛋白3(IMP3),又名K同源决定域蛋白,在癌和L523S细胞中呈过表达,IMP家族中的成员,而且已经发现它在区分
Based on the Breslow depth of primary melanoma, sentinel lymph node biopsies are considered staging criteria for cutaneous melanoma and are one of the most important prognostic factors. However, histological analysis of specimens is difficult when benign nevus cells in lymph nodes are similar to metastatic melanoma cells. Insulin-like growth factor II messenger RNA binding protein 3 (IMP3), also known as a K-homeodogenic protein, is overexpressed in cancer and L523S cells, a member of the IMP family, and it has been found that it differentiates
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