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目的:观察辛伐他汀联合宁心汤治疗冠心病并高血脂的临床效果。方法:将我院2013年3月~2015年3月收治的80例冠心病并高血脂患者作为研究对象,按完全双盲法分为对照组与观察组各40例。2组均接受常规治疗,对照组采用辛伐他汀干预,观察组则在此基础上加用宁心汤处理,比较2组心电图疗效及血脂水平的变化。结果:1观察组治疗总有效率为95.0%,对照组总有效率为72.5%,两组心电图有效率对比差异有统计学意义(P<0.05);2治疗后,观察组TG、LDL-C、TC水平分别为(1.1±0.1)mmol/L、(2.8±0.4)mmol/L、(3.4±0.2)mmol/L,较治疗前明显降低,与对照组相比差异有统计学意义(P<0.05);3治疗后,观察组LVEF、CO及CI指标分别改善至(90.8±11.4)%、(5.3±0.6)L/min、(4.1±0.4)L/min,与对照组相比差异有统计学意义(P<0.05)。结论:在冠心病并高血脂患者的治疗中,采用辛伐他汀联合宁心汤方案,临床治疗有效率高,患者心功能及血脂指标改善明显,值得推广。
Objective: To observe the clinical effect of simvastatin combined with ningxin decoction in treating coronary heart disease and hyperlipidemia. Methods: Eighty patients with coronary heart disease and hyperlipemia admitted from March 2013 to March 2015 in our hospital were enrolled in this study. All patients were divided into control group and observation group according to complete double-blind method. Both groups received routine treatment, the control group with simvastatin intervention, the observation group is based on the use of Ning Xin Tang treatment, compared two groups of ECG efficacy and blood lipid levels. Results: 1 The total effective rate of observation group was 95.0%, the total effective rate of control group was 72.5%, there was significant difference between the two groups (P <0.05); After treatment, TG, LDL-C (1.1 ± 0.1) mmol / L and (2.8 ± 0.4) mmol / L and (3.4 ± 0.2) mmol / L respectively, which were significantly lower than those before treatment (P <0.05). After treatment, the LVEF, CO and CI of the observation group were improved to (90.8 ± 11.4)%, (5.3 ± 0.6) L / min and (4.1 ± 0.4) L / There was statistical significance (P <0.05). Conclusion: In the treatment of patients with coronary heart disease and hyperlipidemia, the combination of simvastatin and ningxin decoction has the advantages of high clinical efficiency, obvious improvement of cardiac function and blood lipid index, and worthy of promotion.