论文部分内容阅读
目的：观察放线共生放线杆菌表面相关物质对Ｍｃ３Ｔ３－Ｅ１细胞的ＤＮＡ合成和细胞周期的影响。方法：应用流式细胞仪技术。结果：１００μｇ／ｍｌ组明显抑制细胞ＤＮＡ合成，细胞增殖指数（Ｓ＋Ｇ２Ｍ）％降低（Ｐ＜０．０５）。结论：此物质不仅抑制细胞的分裂、增殖，而且还抑制细胞的ＤＮＡ合成，提示其在牙周病骨吸收过程中起着重要作用
Objective: To observe the effects of Actinobacillus actinomycetes surface-related substances on the DNA synthesis and cell cycle of Mc3T3-E1 cells. Methods: The application of flow cytometry technology. Results: 100μg / ml group significantly inhibited DNA synthesis and the cell proliferation index (S + G2M)% decreased (P <0.05). Conclusion: The substance not only inhibits the cell division and proliferation, but also inhibits the DNA synthesis of cells, suggesting that it plays an important role in the process of periodontal bone resorption