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本文对１３６株ＣＮＳ进行ＡＰＩ分类，ＰＣＲ检测ＭＲＣＮＳ及纸片法药敏测定，结果表明ＣＮＳ感染以表皮葡萄球菌（占６１７６％）、溶血葡萄球菌（占２５０％）为主。ＭＲＣＮＳ已成为院内感染重要病原菌，占ＣＮＳ的７８７％。纸片法药敏结果显示ＣＮＳ对青霉素类、喹诺酮类、大环内酯类、磷霉素、氯霉素耐药较高，约为４０～７０％，有些高达８０～９０％，而对利福平、米诺环素、阿米卡星、奈替米星及某些头孢菌素类耐药率较低，对万古霉素、去甲万古霉素全部敏感，且ＭＲＣＮＳ的耐药率显著高于ＭＳＣＮＳ（ｐ＜０００１）。
In this paper, 136 CNS were API classification, PCR detection of MRCNS and disk method drug susceptibility determination, the results show that CNS infection with Staphylococcus epidermidis (61 76%), Staphylococcus hemolyticus (25 0%) based. MRCNS has become an important pathogen of nosocomial infection, accounting for 78.7% of CNS. The susceptibility test showed that CNS was resistant to penicillins, quinolones, macrolides, fosfomycin and chloramphenicol, accounting for 40-70% and some as high as 80-90% Fuping, minocycline, amikacin, netilmicin, and some cephalosporins were less susceptible to vancomycin and norvancomycin, and MRCNS had a significant resistance rate Higher than MSCNS (p <0001).