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目的:观察自发性知觉经络反应(ASMR)的脑电频谱特征，从神经电生理学角度揭示ASMR的神经机制。方法:自2019年6月至12月对从南方医科大学在校学生中招募的33例健康受试者随机播放ASMR音频和白噪音，同时采集受试者听音频过程中的情绪反应以及脑电δ、θ和α节律的功率信息。结果:16例受试者听ASMR音频时触发ASMR，纳入ASMR组；17例受试者未触发ASMR，纳入对照组。在听ASMR音频时，与对照组相比，ASMR组受试者的愉悦度及δ、θ节律的功率明显更强，差异均有统计学意义(n P<0.05)；在ASMR组中，受试者听ASMR音频时的愉悦度及δ、θ节律的功率均明显高于白噪音，差异均有统计学意义(n P<0.05)。n 结论:ASMR可以提高个体的愉悦度，其机制可能与δ、θ节律的功率增强有关。“,”Objective:To explore the electroencephalography (EEG) spectrum features of autonomous sensory meridian response (ASMR), which could provide an important bias for revealing the mechanism of ASMR from the perspective of electric neurophysiology.Methods:Thirty-three healthy subjects were recruited from Southern Medical University from June 2019 to December 2019. Emotional response and power information of δ, θ and α rhythms of these subjects when listening to ASMR audio and white noise were recorded.Results:ASMR response was triggered in 16 subjects (ASMR group) when listening to ASMR audio; and ASMR response was not triggered in 17 subjects (control group). As compared with the control group, the subjects in the ASMR group were more pleasant when listening to ASMR audio, accompanied by significantly increased power of δ and θ rhythms ( n P<0.05). As compared with white noise, ASMR audio could promote pleasure and power of δ and θ rhythms in the ASMR group, with significant differences (n P<0.05).n Conclusion:ASMR could promote pleasure, and the mechanism may be related to the enhancement of power of δ and θ rhythms.