论文部分内容阅读
目的研究心力衰竭治疗前后心肌酶(CK-MB)和肌钙蛋白T(c Tn T)及C反应蛋白(CRP)水平变化,为临床诊断与治疗提供借鉴。方法 80例心力衰竭患者作为实验组,给予坎地沙坦联合马来酸依那普利缓释片治疗。选择80例身体健康者作为对照组,对患者治疗前后的CK-MB、c Tn T、CRP水平进行检测。分析两组的检测数据并比较。结果实验组治疗后CRP水平为(2.24±0.33)mg/L,对照组CRP水平为(2.25±1.12)mg/L,两组比较差异无统计学意义(P>0.05)。实验组治疗后c Tn T为(0.21±0.02)ng/dl,CK-MB(21.88±27.30)ng/dl,均高于对照组的(0.02±0.01)、(8.31±2.22)ng/dl,差异有统计学意义(P<0.05)。结论心力衰竭患者治疗前后CK-MB和c Tn T及CRP水平变化是患者病情变化的重要反映,检测c Tn T、CK-MB、CRP水平对判断临床治疗效果具有重要意义。
Objective To study the changes of myocardial enzymes (CK-MB) and troponin T (cTn T) and C-reactive protein (CRP) levels before and after treatment of heart failure and provide references for clinical diagnosis and treatment. Methods Eighty patients with heart failure were treated with candesartan and enalapril maleate as experimental group. Eighty healthy individuals were selected as the control group, and the levels of CK-MB, cTn T and CRP before and after treatment were measured. Analysis of the two groups of test data and comparison. Results The level of CRP in the experimental group was (2.24 ± 0.33) mg / L after treatment and (2.25 ± 1.12) mg / L in the control group. There was no significant difference between the two groups (P> 0.05). The levels of cTn T in the experimental group were (0.21 ± 0.02) ng / dl and (21.88 ± 27.30) ng / dL, respectively, higher than those in the control group (0.02 ± 0.01 vs 8.31 ± 2.22 ng / dl, The difference was statistically significant (P <0.05). Conclusion The changes of CK-MB, cTn T and CRP before and after treatment in patients with heart failure are the important reflection of the patient’s condition. Detecting the levels of cTn T, CK-MB and CRP is of great significance in judging the clinical effect.