论文部分内容阅读
目的对子宫内膜增生患者接受米非司酮联合小剂量甲基睾丸素的临床治疗效果予以评价,为子宫内膜增生的临床治疗提供科学的依据。方法 35例子宫内膜增生患者,患者使用米非司酮进行为期3个月的治疗,然后使用小剂量甲基睾丸素治疗2周。计算治疗后患者的平均子宫内膜厚度,统计本组治疗的整体有效率。结果 35例患者治疗前子宫内膜厚度平均为(8.79±0.97)mm;治疗后其子宫内膜的平均厚度为(4.36±0.37)mm,治疗前后比较差异有统计学意义(P<0.05)。治疗6个月后,33例患者病情得到了有效的控制,病情痊愈,治疗有效率达94.29%(33/35)。在用药期间,35例患者均出现了停经现象,用药结束后52~73 d逐渐得到了恢复。结论米非司酮伍小剂量甲基睾丸素治疗子宫内膜增生效果显著,可显著提高患者的生活质量水平,因而具有较高的临床应用价值。
Objective To evaluate the clinical efficacy of mifepristone combined with low-dose methyltestosterone in patients with endometrial hyperplasia and provide a scientific basis for the clinical treatment of endometrial hyperplasia. Methods Thirty-five patients with endometrial hyperplasia were treated with mifepristone for 3 months and then treated with low-dose methyltestosterone for 2 weeks. Calculate the mean endometrial thickness of patients after treatment, statistics of the overall efficiency of the treatment group. Results The average thickness of endometrium of 35 patients before treatment was (8.79 ± 0.97) mm. The average thickness of endometrium was (4.36 ± 0.37) mm after treatment. The difference was statistically significant before and after treatment (P <0.05). After 6 months of treatment, the condition of 33 patients was effectively controlled and the condition recovered. The effective rate of treatment was 94.29% (33/35). During the medication, all 35 patients experienced menopause, and gradually recovered from 52 to 73 days after treatment. Conclusion The low dose of methylprednisolone treatment of endometrial hyperplasia significant effect, can significantly improve the quality of life of patients, which has high clinical value.