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目的观察呼吸机联合大剂量氨溴索治疗新生儿呼吸窘迫综合征效果。方法 74例新生儿呼吸窘迫综合征患儿,随机分为研究组和对照组,各37例。均予以综合治疗并应用常频呼吸机,对照组予以肺泡表面活性物质治疗,研究组予以大剂量氨溴索治疗。观察两组患儿临床效果及肺炎并发情况。结果两组患儿临床治疗效果比较,差异无统计学意义(P>0.05);研究组住院总费用(23005.6±1365.4)元,并发肺炎8例(21.6%),均优于对照组的(29986.5±5431.6)元、16例(43.2%)(P<0.05)。结论呼吸机与大剂量氨溴索治疗新生儿呼吸窘迫综合征,可在保证治疗效果的同时,还可节省医疗费用,减少肺炎发生,缩短肺炎疗程,在临床治疗中具有重要意义。
Objective To observe the effects of ventilator combined with high-dose ambroxol on neonatal respiratory distress syndrome. Methods 74 neonates with respiratory distress syndrome were randomly divided into study group and control group, with 37 cases in each group. All patients were treated with common-frequency ventilator and alveolar surfactant in the control group. The study group was given high-dose ambroxol. The clinical effects and the complications of pneumonia in both groups were observed. Results There was no significant difference between two groups (P> 0.05). The total cost of hospitalization (23005.6 ± 1365.4) yuan in the study group and 8 cases (21.6%) with pneumonia were significantly higher than those in the control group (29986.5 ± 5431.6) yuan, 16 cases (43.2%) (P <0.05). Conclusion Ventilator and high-dose ambroxol treatment of neonatal respiratory distress syndrome can not only ensure the therapeutic effect, but also save medical costs, reduce the occurrence of pneumonia and shorten the course of pneumonia, which is of great significance in clinical treatment.