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目的:探讨I~(125)粒子植入治疗直肠癌根治术后放化疗后盆腔照射野内复发或伴远处转移患者的疗效。方法:对直肠癌根治性术后复发转移的部分患者给予I~(125)粒子植入治疗。结果:治疗2个月后粒子植入组患者疼痛程度较治疗前明显减轻(P<0.01)。治疗6个月后粒子植入组盆腔肿瘤缓解率、3年总体生存率比较,差异具有统计学意义(P<0.05)。结论:盆腔种植放射性粒子放疗可提高直肠癌术后放射野内复发患者生活质量,降低并发症发生风险。
Objective: To investigate the effect of I ~ (125) particle implantation in the treatment of rectal recurrence or distant metastasis after radiotherapy and chemotherapy in patients with rectal cancer after radical operation. Methods: I ~ (125) seeds were implanted in some patients with recurrent and metastasis of radical resection of rectal cancer. Results: After 2 months of treatment, the degree of pain in the group of particle implantation was significantly reduced compared with that before treatment (P <0.01). The pelvic tumor remission rate and the 3-year overall survival rate after 6 months of treatment were statistically significant (P <0.05). Conclusion: Pelvic radiotherapy can improve the quality of life of patients with recurrent rectal cancer after radiation and reduce the risk of complications.