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一、概述肿瘤免疫疗法已有80～90年的历史。过去由于对肿瘤免疫的实质不甚了解,仅局限于体液免疫的研究,致使肿瘤免疫进展极为缓慢。近10余年,由于免疫学的迅速进展,也促进了肿瘤免疫的发展。临床上对肿瘤免疫亦给予3极大的关注。其原因在于,①伴随免疫学的显著进步,采用了崭新的技术,发现肿瘤相关抗原(Tumor associated antigen,TAA)不仅存在于动物肿瘤,人类肿瘤上也被确认;②基于对肿瘤相关抗原的免疫反应,在某些动物肿瘤
I. Overview Cancer immunotherapy has been 80 to 90 years old. In the past, due to the lack of understanding of the nature of tumor immunity, the study was limited to humoral immunity, resulting in extremely slow tumor immunity. In the past more than 10 years, due to the rapid progress of immunology, the development of tumor immunity has also been promoted. Clinical attention has also been given to tumor immunity. The reason is that 1 accompanied by significant advances in immunology, using a new technology, found that Tumor associated antigen (Tumor associated antigen, TAA) is not only found in animal tumors, human tumors have also been confirmed; 2 based on immunity to tumor-associated antigens Response, in some animal tumors