OBJECTIVE: To investigate the activations cyclooxygenase-2 (COX-2)/5-1ipoxygenase (5-LO) pathways of arachidonic acid (AA) metabolism and the protective effects of 13-methyltetradecanoic acid (13-MTD)
Hypoestes purpurea R.Brown (H.P.)(六角英), Procumbent Tridax (P.T.)(長柄菊), Emilia sonchifolia (E.S.)(一點紅) and Tithonia Diversifolia (T.D.)(五爪金英) are usually used in healthy tea.The healthy tea is associat
Spinal cord injury (SCI)-induced secondary oxidative stress associates with a clinical complication and high mortality.Treatments to improve the neurological outcome of secondary injury are considered
ClC-3 chloride channel, plays an important role in the regulation of cell volume, proliferation and apoptosis.Preadipocytes of type 2 diabetes show a tendency to enhanced apoptosis.We hypothesized tha
Cardiac side population cells (CSPs) are promising cell resource for the regeneration in diseased heart as intrinsic cardiac stem cells.However the relative low ratio of CSPs in the heart limited the
To evaluate the role of the DNA methylation of the CpG island within the PON1 promoter on the clinical efficacy of the dual-antiplatelet therapy of aspirin and clopidogrel in patients with CAD after p
Aims: Pellinol is an evolutionally conserved immune regulator and participates in the regulation of activation of Toll-like receptor/intefleukin-1 receptor (TLR/IL-1R)-mediated signaling.TLR/IL-1R sig
Myocardial fibrosis plays a critical role in the process of diabetic cardiac remolding.MicroRNAs are endogenous, small non-coding RNAs that negatively regulate gene expression in diverse biological an
OBJECTIVE: To investigate whether Clq/TNF-related protein (CTRP) 6 is involved in vascular smooth muscle cell (VSMC) migration and neointima formation in response to vascular injury.METHODS:Male Sprag
目的:观察成体大鼠局灶性脑缺血后,激活的小胶质细胞是否如同胚胎时期和生后早期大鼠脑内的阿米巴样小胶质细胞一样,再次表达血管紧张素Ⅱ(AngⅡ)及其受体(AT1和AT2受体),且表达变化规律如何;研究AngⅡ及其受体与脑缺血及激活的小胶质细胞三者之间的关系,探讨脑缺血的发病机理.方法:采用微创开颅法建立大鼠大脑中动脉闭塞(MCAO)模型,将81只成年雄性SD大鼠分为正常对照组(n=9),假手术组(n