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  5. Encapsulation of doxorubicin within lactobionic acid-modified multifunctional poly(amidoamine) dendr

Encapsulation of doxorubicin within lactobionic acid-modified multifunctional poly(amidoamine) dendr

来源 :The Third Symposium on Innovative Polymers for Controlled De | 被引量 : 0次 | 上传用户：adf2008
【摘 要】
：
Current anticancer drugs used in the clinic suffer trom problems such as poor water solubility,rapid clearance,and nonspecific distribution in the normal tissue.Recent advances in dendrimer nanotechno
【作 者】
：
Fanfan Fu Shihui Wen Jingyi Zhu Xiangyang Shi 
【机 构】
：
College of Chemistry,Chemical Engineering and Biotechnology,Donghua University,Shanghai 201620,China
【出 处】
：
The Third Symposium on Innovative Polymers for Controlled De
【发表日期】
：
2014年6期
【关键词】
：
dendrimers doxorubicin PEGylation encapsulation targeted cancer therapy 
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　　Current anticancer drugs used in the clinic suffer trom problems such as poor water solubility,rapid clearance,and nonspecific distribution in the normal tissue.Recent advances in dendrimer nanotechnology have shown that it is possible to develop a carrier system that can specifically target cancer cells via a receptor-mediated active targeting strategy [1].
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