【摘 要】
：
Objectives.-To examine the association between glycemic control and the degree of cognitive impairment in older patients with type 2 diabetes.Our hypothesis is less cognitive impairment is associated
【机 构】
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Aged Care Services Department, Heidelberg Repatriation Hospital, Australia ;Department of Medicine,
【出 处】
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MIT`s 1st Annual World Congress of Diabetes-2012(2012第一届糖尿病大
论文部分内容阅读
Objectives.-To examine the association between glycemic control and the degree of cognitive impairment in older patients with type 2 diabetes.Our hypothesis is less cognitive impairment is associated with better glycemic control.Design.-Cross-sectional study.Setting.-Patients in subacute aged care unit at Heidelberg Repatriation hospital in Melboume, Australia.Participants.-A total of 142 subjects aged 63 to 96 with prior diagnosed type 2 diabetes.Methods.-Cognitive function was assessed using the Mini Mental State Examination (MMSE) and glycemic control was measured by a validated method.Results.-An inverse correlation was observed between the MMSE score and HbA1c levels (r =0.239, P =0.004), which persisted after controlling for variables of interest including age, gender, BMI, diabetes duration, years of education and other co-morbidities.A 1-point-higherMMSE score was associated with a 0.239 lower HbA1 c value (P =0.001).Conclusion.-This study suggests that better glycemic control is associated with less cognitive impairment in elderly patients with type 2 diabetes.
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