黄连碱对异丙肾上腺素致心肌缺血损伤的保护作用

来源 :第九届海峡两岸心血管科学研讨会暨首届台湾南部国际心脑血管科学研讨会 | 被引量 : 0次 | 上传用户：yanghao_haohao

【摘要】

：

目的:黄连为常用中药,具有清热燥湿,泻火解毒之功效.现代研究表明,黄连具抗菌、降血糖、保护脑损伤、抗血小板聚集及抗溃疡等作用.黄连碱是从黄连中提取的异喹啉类生物碱,具有抗病毒、抗真菌、抗氧化、抑制平滑肌细胞增殖等作用.但是目前还没有关于黄连碱舒张血管、保护心脏作用的报道,本文将研究黄连碱对异丙肾上腺素(Isoproterenol,ISO)致大鼠心肌缺血损伤的保护作用和机制.

【作者】

：

方莲花宫丽丽郭晶王守宝王月华秦海林杜冠华

【机构】

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中国医学科学院北京协和医学院药物研究所药物靶点研究与新药筛选北京市重点实验室,北京100050 首

【出处】

：

第九届海峡两岸心血管科学研讨会暨首届台湾南部国际心脑血管科学研讨会

【发表日期】

：

2013年4期

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黄连碱对异丙肾上腺素致心肌缺血损伤的保护作用

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