Epigenetic Modification Regulates the Attention Deficit & Hyperactivity Disorder Associated with

• 作 者: Hui-LiWang[1]YiXu[1]Di-YunRuan[2]DeWu[3]ManLuo[1]GuangxiangZhang[4]BinYang[5]
• 机 构: School of Biotechnology and Food Engineering,Hefei University of Technology,Hefei,Anhui Province,230
• 出 处: 中国毒理学会第七次全国毒理学大会暨第八届湖北科技论坛
• 发表日期: 2015年期

　　Attention deficit & hyperactivity disorder (ADHD) was a common neurobehavioral disease defined by inattention, hyperactivity and impulsivity.Its prevalence in the school-aged children could reach up to 3-10 %, making it one of the most common psychiatric disorders in children and adolescents.In China, ADHD has become a severe impairment detrimental for children health as well as educational and social development.Of note, approximately 65 % of ADHD children could have their syndromes persisted into adulthood, resulting in a 4 % of infected population.The etiology of ADHD was not only ascribed to heritable factors involved in dopaminergic systems, but also the environmental influences at early life during individual development.