Host Genetics and HIV-I Resistance

来源 :2006中国天津世界艾滋病日科技会议 | 被引量 : 0次 | 上传用户：jhiphop

【摘要】

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【作者】

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Kalpana Luthra Naveet Wig Tripathi BM Manju Bala Romsha Gupta RB Omkar Choudhary Alok Choudhary Vishwas Tripathy Kavita Rajshekhar Rama Bhasin

【机构】

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Department of Biochemistry, All India Insititute of Medical sciences, India

【出处】

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2006中国天津世界艾滋病日科技会议

【发表日期】

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2006年12期

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　　Several epidemiological studies reveal that there is a great variation in the susceptibility of individuals of different populations to HIV-1 infection and or disease progression.Host genetic variations play crucial roles in influencing HIV-1 infection and disease progression.Mutations in chemokine receptors CCR5 (CCR5 D3f32),CCR2 (CCR2-64I) anl stromal derived factor SDF-1 (SDF-1-3A) are known to have protective effects against HIV-1 infection and disease progression.We studied the three locus genotype frequency distribution in 500 healthy northern Indians.

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Host Genetics and HIV-I Resistance

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