HIV-Ⅰ Vpr as A Determinant of Cytopathicity in Vivo

来源 :2006中国天津世界艾滋病日科技会议 | 被引量 : 0次 | 上传用户:zhouxiaoqing1003
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  HIV-Ⅰ vpr induces cell cycle arrest in G2 and subsequent apoptosis in infected lymphocytes and human cell lines.We have previously reported that both G2 arrest and apoptosis induced by Vpr are signaled through the ATR DNA damage pathway.
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