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EEG biofeedback or neurofeedback is an operant conditioning procedure in which patients learn to improve functional activities of brain.It is a promising tool for treating dysregulation of central nervous system.Additionally,recent progress has been made in understanding neural mechanism of neurofeedback,such as up-regulation of functional connectivity and induction of microstructural changes of gray and white matter.Integrated EEG and real time functional MRI imaging allows users to self-control electrical and hemodynamic activities of brain simultaneously.But evidence for its benefit in adult psychiatric patient is supported largely by case reports and uncontrolled studies.