【摘 要】
:
The non-classical HLA class I antigen HLA-G has been suggested to be part of strategies for tumor cells to avoid from host immunosurveillance.Aberrant HLA-G expression was frequently detected in metas
【机 构】
:
Medical Research Center, Taizhou Hospital of Zhejiang Province China
论文部分内容阅读
The non-classical HLA class I antigen HLA-G has been suggested to be part of strategies for tumor cells to avoid from host immunosurveillance.Aberrant HLA-G expression was frequently detected in metastic or invasive tumor sites; however, mechanisms of HLA-G expression in malignancy metastasis have yet to be explored.
其他文献
Nasopharyngeal carcinoma (NPC) is a malignant tumor originating in the squamous epithelium.Elevated DNA methyltransferase 1 (DNMT1) expression was previously detected in NPC tumors indicating that abe
FBXW7 is a general tumor suppressor and its mutations have been found in a variety of human cancers.Particularly, FBXW7 mutations occur in nearly 10-15% of colorectal cancer (CRC), ranking it the four
To identify potential microRNA (miRNA) links between Smad3, a mediator of TGF-β (transforming growth factor-β) signaling, and E-cadherin, we characterized the miRNA profiles of two gastric cancer cell
The transcription factor E2F, the main target of the tumor suppressor RB, plays central roles in activation of growth-promoting genes through physiological inactivation of RB by growth stimulation.E2F
CD44 is a cell-surface glycoprotein, which participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis.However,
Carbonic anhydrase (CA) inhibitors have been proposed as a new class of antitumor agents.The expression of CA Ⅸ, VEGF and the activity of caspase-3 were evaluated in human renal cell carcinoma biopsie
Liver cancer or hepatocellular carcinoma is one of the leading causes of cancer-related deaths.Conventional chemotherapies are limited by the development of drug resistance and various side effects.Be
Patients with neuroblastoma due to N-Myc oncogene-amplification die of tumour metastasis.However, little is known about how N-Myc induces cell migration, invasion and metastasis.The histone demethylas
MicroRNAs (miRNAs) regulate tumor progression and invasion via direct interaction with target messenger RNAs (mRNAs).We defined miRNAs involved in cancer metastasis (metastamirs) using an established
The transcription factor signal transducer and activator of transcription 3 (STAT3) contributes to cell proliferation, apoptosis, and motility in human cancer cells.We aim to elucidate the function of