【摘 要】
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The transcription factor signal transducer and activator of transcription 3 (STAT3) contributes to cell proliferation, apoptosis, and motility in human cancer cells.We aim to elucidate the function of
【机 构】
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Key Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medica of the State Administratio
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The transcription factor signal transducer and activator of transcription 3 (STAT3) contributes to cell proliferation, apoptosis, and motility in human cancer cells.We aim to elucidate the function of STAT3 in esophageal carcinogenesis process and molecular mechanisms.We showed that hyperactivated STAT3 in esophageal carcinogenesis tissues correlated with the overexpression of octamer transcription factor-1 (Oct-l).High STAT3 phosphorylation correlated with shorter survival compared to low STAT3 phosphorylation.
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