Targeting SIRT1 in Huntington's disease: rationale and current status

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：g8y99

【摘要】

：

Huntingtons disease (HD) is an autosomal dominant hereditary disease caused by a trinucleotide repeat mutation in the huntingtin gene that results in an increased number of glutamine residues in the N

【作者】

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Wen-zhen DUAN

【机构】

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Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Departments of Neuroscie

【出处】

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The 12th Meeting of the Asia Pacific Federation of Pharmacol

【发表日期】

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2013年4期

【关键词】

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Sirt1 BDNF TrkB Huntington's disease neurodegeneration

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