Many DNA base repairs and modifications, such as DNA methylation/demethylation, deamination, and hydroxylation, are known to occur extrahelically with the targe
Isoprenoids, the most structurally and functionally diverse group of metabolites with more than 50,000 members in nature, are constructed from two precursors, i
Fipronil, which act on insect GABAA receptor was an important insecticide for crop protection.However, the observed high toxicity on fish deeply limited its app
The heat-shock protein DegP is essential for the survival of Escherichia coli cells at elevated temperatures.Substrate binding transforms hexameric DegP into la
Water was found can bridge the binding between quinazolines and epidermal growth factor receptor (EGFR) through hydrogen bonding network at the binding pocket.T