New Sight into DegPs Role in Protein Quality Control

来源 :第八届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：stone88822

【摘要】

：

The heat-shock protein DegP is essential for the survival of Escherichia coli cells at elevated temperatures.Substrate binding transforms hexameric DegP into la

【作者】

：

Zhi-Xin Lyu Xin-Sheng Zhao

【机构】

：

BeijingNationalLaboratoryforMolecularSciences,StateKeyLaboratoryforStructuralChemistryofUnstableandS

【出处】

：

第八届全国化学生物学学术会议

【发表日期】

：

2013年9期

【关键词】

：

Protease Chaperone Protein quality control Single molecule FRET

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The heat-shock protein DegP is essential for the survival of Escherichia coli cells at elevated temperatures.Substrate binding transforms hexameric DegP into large, catalytically active multimers.However, whether DegP performs chaperone activity has long been under debate.

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New Sight into DegPs Role in Protein Quality Control

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