【摘 要】
：
Mechanobiology is indispensable to all living creatures ranging from bacteria to human beings because every living thing continually experiences mechanical stimuli,not only exogenous but also endogeno
【机 构】
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Cardiovascular Physiology Okayama University Japan
【出 处】
：
2008中国深圳蛋白质和多肽科学大会
论文部分内容阅读
Mechanobiology is indispensable to all living creatures ranging from bacteria to human beings because every living thing continually experiences mechanical stimuli,not only exogenous but also endogenous,and responds appropriately to these stimuli.At the cellular level,there are three major mechanical stresses,such as,stretch,shear stress and pressure.We have been intensively investigating systems to apply these mechanical environments to cells.Analysis of these responses is critical to understand the mechanisms and regulation of diverse physiological processes such as arterial and regulation,sensory perception,muscle development,and so on.Therefore,to study mechanobiology,we took the advantage of the polydimethysiloxane (PDMS) based technology,which is called soft lithography.In this lecture,following topics are discussed; Cell Stretching System,Shear Stress Sytem,and Cell Patterning using Microcontact Printing System.
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