Nitric Oxide/Caveolin-l/MMP Pathway: A novel therapeutic strategy for drug discovery from herbal med

来源 :The 18th Congress of the International Federation of Associa | 被引量 : 0次 | 上传用户：jinshu

【摘要】

：

【作者】

：

Jiangang Shen Yong Gu

【机构】

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School of Chinese Medicine, University of Hong Kong, Hong Kong, Hong Kong SAR, China

【出处】

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The 18th Congress of the International Federation of Associa

【发表日期】

：

2014年8期

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We investigated the expressions of cav-1 and NOS, the production of NO and peroxynitrite, activation of MMP-9,tight-junction (T J) protein, BBB permeability and infarction volume in rat and mouse models of cerebral ischemia-reperfusion injury in vivo and hypoxic rat brain microvascular endothelial cells (BMECs) in vitro.CG (60 μmol/kg, i.p.) was used at 15 min before ischemia.

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Nitric Oxide/Caveolin-l/MMP Pathway: A novel therapeutic strategy for drug discovery from herbal med

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