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In addition to learning and memory impairments, diabetes may also brings about neuronal loss in different regions of the brain specially hippocampus.In this line, the present study was conducted to investigate the effects of type 1 (T1D) and type 2 (T2D) diabetes on cognitive function and hippocampal neuronal density in rat.Three groups of male Wistar rats (No=6) were regarded as control, T1D and T2D.