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  5. Alterations in the neural circuits from peripheral afferents to the spinal cord: Possible implicatio

Alterations in the neural circuits from peripheral afferents to the spinal cord: Possible implicatio

来源 :The 18th Congress of the International Federation of Associa | 被引量 : 0次 | 上传用户：limida
【摘 要】
：
Diabetic polyneuropathy (DPN) presents as a wide variety of sensorimotor symptoms.Changes in the neural circuits may occur in the early stages in diabetes and are implicated in the development of DPN.
【作 者】
：
Zhenzhen Kou Hui Li Yunqing Li 
【机 构】
：
Department of Anatomy, Histology and Embryology, K.K.Leung Brain Research Centre, The Fourth Militar
【出 处】
：
The 18th Congress of the International Federation of Associa
【发表日期】
：
2014年8期
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论文部分内容阅读
Diabetic polyneuropathy (DPN) presents as a wide variety of sensorimotor symptoms.Changes in the neural circuits may occur in the early stages in diabetes and are implicated in the development of DPN.Therefore, we aimed to detect changes in the expression of isolectin B4 (IB4, the marker for nonpeptidergic unmyelinated fibers and their cell bodies) and calcitonin gene-related peptide (CGRP, the marker for peptidergic fibers and their cell bodies) in the dorsal root ganglion (DRG) and spinal cord of streptozotocin (STZ)-induced type 1 diabetic rats showing alterations in sensory and motor function.
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