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Introduction: Shoulder osteoarthritis can lead to depression, anxiety, activity limitations, and job-performance problems.Total shoulder arthroplasty and Hemi-arthroplasty are both treatment choices for end-stage shoulders osteoarthritis.The decision of whether to use TSA or HA carries some controversy.Objectives: to determine the effects of TSA versus HA for shoulder osteoarthritis.Methods: We conducted a search for clinical studies published in any language in the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and other databases until Dec.2012.Randomized and quasi-randomized controlled clinical studies evaluating different methods were included.At least two review authors independently performed study selection and data collection and extraction.We applied the Revman 5.1 for statistical analysis.