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有人认为内源性鸦片类与经前期紧张(PMT)有关,但缺乏直接证据,用强效鸦片拮抗剂纳络酮的实验表明正常月经周期黄体期内源性鸦片类活性增强,另有报告周期中期内源性鸦片类血浓度增高。本研究中作者测定PMT病人血β-内啡肽的免疫反应性(irβ-E)。研究包括12例PMT和14例对照妇女,平均年龄分别为39和36岁,平均体重为芬兰妇女标准体重的103%和99%,平均周期长度为28±0.8天和27±0.7天,二组分别有6例和13例为经产妇。12例PMT病人的经前期症状为:乳房胀痛(12例),腹胀(11例)、头痛(5例)、腹痛(5例)、激动(12例)、抑郁(7例)、食欲增加(5例)、焦虑
Some people think that the endogenous opioids and premenstrual tension (PMT), but the lack of direct evidence, with a powerful opiate antagonist naloxone experiments showed that the normal menstrual cycle luteal phase endogenous opioid activity increased, and another reporting cycle Mid-term increase in endogenous opioid blood concentration. The authors of this study determined the immunoreactivity (β-E) of blood in patients with PMT. The study included 12 PMTs and 14 control women with mean ages of 39 and 36 years, mean body weights of 103% and 99%, respectively, of Finnish women with mean durations of 28 ± 0.8 days and 27 ± 0.7 days, There are 6 cases and 13 cases of maternal. Premenstrual symptoms in 12 patients with PMT were breast tenderness (12 cases), abdominal distension (11 cases), headache (5 cases), abdominal pain (5 cases), agitation (12 cases), depression (7 cases), increased appetite (5 cases), anxiety