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绝经后出血是老年妇女妇科恶性肿瘤的征兆,绝经后期妇女卵巢尚未完全萎缩,仍有部分分泌雌激素的功能。另外,由于老化、肥胖致卵巢间质和肾上腺的雌酮量的增加,都可导致子宫出血。因此鉴别绝经后出血原因是很重要的。我们对126例绝经后出血妇女(出血组)和52例绝经后健康妇女(对照组)进行了血清 E_2、FSH、LH 放免测定,同时通过阴道侧壁连续刮片,观察雌激素水平,并做了分段诊刮宫内膜病理组织学检查。两组结果比较表明:出血组血清中 E_2含量,各年限均值超过正常绝经后妇女的6.5倍,两组的差异非常显著(P<0.01);随绝经年限延长,E_2水平有逐渐下降趋势,但仍显著高
Postmenopausal bleeding is an indication of gynecologic malignancies in older women, and the ovaries of postmenopausal women have not yet completely shrunk, with some still having the function of secreting estrogen. In addition, due to aging, obesity increases the amount of estrogen in the ovarian stroma and adrenal gland that can cause bleeding in the uterus. Therefore, the identification of causes of postmenopausal bleeding is very important. We measured 126 cases of postmenopausal bleeding women (bleeding group) and 52 cases of postmenopausal healthy women (control group) serum E2, FSH, LH radioimmunoassay, while continuous vaginal wall scraping sheet to observe the estrogen levels, and do A sub-curettage endometrial histopathology. The results of the two groups showed that the E_2 content in the serum of the hemorrhage group was 6.5 times more than that of the normal postmenopausal women, the difference between the two groups was significant (P <0.01). With the extension of menopause, E 2 level gradually decreased, Still significantly higher