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1981年7月1日至1983年7月30日美国Colo-rado,Denver大学三级产/儿中心医院围产儿死亡总数172例,其中64例死胎、108例新生儿死亡。经家属同意共作尸检139例(死胎52例、新生儿死亡87例),尸检率81%。尸检前由临床遗传学家和解剖助手复习其临床情况,尸检时作全面解剖学检查(包括脑检查)、胎盘的肉眼和镜下检查、除腐烂外一律作各脏器的组织学检查,此外有指征时应作组织培养、染色体分析、全身X线造影、病毒或细菌培养或将组织冰冻以备疑有先天代谢异常时进行生化测定。在死亡分析中将单纯由临床检查确定的死因和尸检分析结果加以比较。
From July 1, 1981 to July 30, 1983, there were 172 cases of perinatal deaths in the tertiary care / tertiary care center of the University of Denver, Colo-rado, United States of America, 64 of which were stillborn and 108 of whom died of neonatal death. A total of 139 autopsy cases (52 stillbirths and 87 neonatal deaths) were made with the consent of their families. The autopsy rate was 81%. Before the autopsy by the clinical geneticists and anatomical aides to review the clinical situation, when the autopsy for a comprehensive anatomical examination (including brain examination), the naked eye and microscopic examination of the placenta, in addition to decay outside the organ for all histological examination, in addition Indications should be made for tissue culture, chromosome analysis, whole body X-ray angiography, virus or bacterial culture or frozen tissue to suspect the presence of inborn errors of metabolism biochemical tests. In the death analysis, the cause of death, which was determined solely by clinical examination, and autopsy analysis were compared.