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妊娠期肝内胆汁淤积症(intrahepatic cholestasis of pre-qanancy.ICP),是妊娠期特有的一种并发症,多发生妊娠中晚期,主要表现为皮肤瘙痒或黄疸以及肝功能异常。其病因不清,该病最大的危害在于其易导致围生儿预后不良,可引起早孕,羊水胎粪污染及产时胎儿窘迫,有报道围生儿死亡率可高达110%。ICP患者的胎死宫内通常发生非常迅速,且发生胎儿窒迫的原因尚未阐明。亦缺乏有效的防治措施。ICP的发病位置往往首先表现为皮肤瘙痒,
Intrahepatic cholestasis of pre-qanancy (ICP), a complication of pregnancy, occurs frequently in the late pregnancy, mainly manifested as itchy skin or jaundice and liver dysfunction. The etiology is unclear, the greatest harm of the disease is that it can easily lead to poor prognosis perinatal children, can cause early pregnancy, amniotic fluid meconium contamination and fetal distress during labor, reported perinatal mortality can be as high as 110%. The most common cause of fetal death in ICP patients is very rapid and the cause of fetal suffocation has not been elucidated. There is also a lack of effective prevention and control measures. The incidence of ICP is often the first to show itchy skin,