新生儿呼吸机相关性肺炎高危因素及病原学分析

• 作 者: 谷广辉
• 机 构: 河南省焦作市妇幼保健院新生儿科,
• 出 处: 中国医疗前沿
• 发表日期: 2013年08期
• 关键词: 呼吸机相关性肺炎 高危因素 病原菌 耐药性

目的探讨新生儿呼吸机相关性肺炎(VAP)的危险因素、病原菌和耐药性特点。方法对2009年1月-2013年1月VAP患儿高危因素、细菌培养及药敏试验回顾性分析。结果 VAP的发病率为32.5%。VAP组孕周<32周、出生体质量<2000g、通气时间>4d,新生儿有较高VAP发病率,病原菌以革兰阴性杆菌为主,且多为耐药菌。结论减少机械通气时间、控制原发病和合理使用抗菌药物,可有效减少VAP的发生。

Objective To investigate the risk factors, pathogens and drug resistance of neonatal ventilator-associated pneumonia (VAP). Methods Retrospective analysis of risk factors, bacterial culture and drug susceptibility test in children with VAP from January 2009 to January 2013. Results The incidence of VAP was 32.5%. VAP group gestational age <32 weeks, birth weight <2000g, ventilation time> 4d, newborns have a higher incidence of VAP, mainly gram-negative bacilli pathogens, and mostly resistant bacteria. Conclusions Reducing the duration of mechanical ventilation, controlling the primary disease and rational use of antimicrobial agents can effectively reduce the incidence of VAP.