【摘 要】
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Objective:To evaluate the antinociceptive activity of the methanol extract of Ricinus communis leaves(MRCL).Methods:Antinociceptive activity was evaluated using
【机 构】
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Department of Pharmacognosy,SVPM's College of Pharmacy,Department of Pharmaceutical Chemistry,SVPM's
【出 处】
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Asian Pacific Journal of Tropical Biomedicine
论文部分内容阅读
Objective:To evaluate the antinociceptive activity of the methanol extract of Ricinus communis leaves(MRCL).Methods:Antinociceptive activity was evaluated using acetic acid induced writhing test,formalin induced paw licking and tail immersion method in mice at doses of 100,125 and 130 mg/kg bw.Results:The results indicated that MRCL exhibited considerable antinociceptive activity against three classical models of pain in mice.Preliminary phytochemical analysis suggested the presence of saponin,steroids and alkaloids.Conclusions:It can be concluded that MRCL possesses antinociceptive potential that may be due to saponin,steroids and alkaloids in it.
Objective: To evaluate the antinociceptive activity of the methanol extract of Ricinus communis leaves (MRCL). Methods: Antinociceptive activity was evaluated using acetic acid induced writhing test, formalin induced paw licking and tail immersion method in mice at doses of 100, 125 and 130 mg / kg bw. Results: The results indicated that MRCL exhibited considerable antinociceptive activity against three classical models of pain in mice. Preliminary Phytochemical analysis suggested the presence of saponin, steroids and alkaloids. Conclusions: It can be concluded that MRCL possesses antinociceptive potential that may be due to saponin, steroids and alkaloids in it.
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