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采用三氮唑核苷、中药和二者联合应用治疗流行性腮腺炎116例,结果三组平均退热时间(h)分别为40.04±6.38、34.62±3.64、18.27±4.21,消肿时间(h)为73.22±4.84、72.31±6.21、47.56±8.10,发现三氮唑核苷与中药治疗流行性腮腺炎在退热、消肿方面差异无显著性,而二种药物联合应用则比单用任何一种为优,差异有高度显著性,提示三氮唑核苷和本中药方有协同抗腮腺炎病毒的作用,加强了抗毒能力,缩短了退热、消肿时间,促进了病情的恢复。对三氮唑核苷的作用机理作了讨论。
The use of ribavirin, traditional Chinese medicine and the combination of the two treatment of 116 cases of mumps, the results of the three groups average antipyretic time (h) were 40.04 ± 6.38,34.62 ± 3.64,18 .27 ± 4.21, swelling time (h) was 73.22 ± 4.84,72.31 ± 6.21,47.56 ± 8.10, and found that ribavirin and Chinese medicine treatment of epidemic parotid gland Inflammation in the antipyretic, swelling was no significant difference, and the two drugs combined application than any one alone is superior, the difference was highly significant, suggesting that ribavirin and the Chinese side have synergistic anti-mumps The role of the virus to strengthen the anti-drug ability to shorten the fever, swelling time, and promote the recovery of the disease. The mechanism of action of ribavirin is discussed.