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目的 :探讨临床表现不同的癫复杂部分性发作 (CPS)与正电子发射断层扫描 (PET)检查病灶定位的相关性。方法 :39例CPS病人经PET、磁共振成像 (MRI)、录像 脑电监测 (Video EEG)检查 ,并对各种检查和临床表现进行比较分析。结果 :PET和EEG二者完全符合和部分符合均为 31% ,15例不符病例中 ,12例为PET有定位价值而EEG不能定位。仅表现为复杂部分性发作而无继发性全身性强直阵挛发作 (GS)者的 71%的病例 ,PET定位于单侧颞叶 ,表现为CPS继发GS者的 81%为颞顶、颞枕区病灶。结论 :CPS不继发全身性发作的患者 ,病灶多局限于一侧颞叶 ,如发作期和发作间期脑电图均正常 ,更应考虑病灶位于颞叶内侧面 ,或边缘系统 ;CPS继发GS的患者病灶多位于颞叶外侧面与顶、枕交界区。
Objective: To investigate the correlation between clinical manifestations of epilepsy complicated partial seizures (CPS) and positron emission tomography (PET) lesions. Methods: Totally 39 CPS patients were examined by PET, MRI and Video EEG, and comparatively analyzed various examinations and clinical manifestations. Results: Both PET and EEG were 31% and 31%, respectively. Of the 15 patients, 12 had PET localization value and EEG could not locate. Only 71% of cases showed complicated partial seizures without secondary tonic-clonic seizures (GS). PET was located in the unilateral temporal lobe and 81% of the secondary CPS patients were temporomandibular, Temporal occipital lesions. CONCLUSIONS: In CPS patients without secondary seizures, the lesions are mostly confined to one side of the temporal lobe. If the EEG is normal during the seizure and interictal seizures, the lesion should be located on the medial surface of the temporal lobe or the limbic system. CPS Following Most of the lesions of patients with GS were located in the temporal lobe and the top of the occipital junction area.