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目的 探讨胃肠道炎性纤维性息肉 (IFP)的诊断、病理学特点及治疗原则。 方法 对1984年～ 1999年经治的 12例IFP的临床和病理资料进行分析总结。 结果 12例均表现为胃肠道粘膜下息肉样肿块 ,以纤维血管增生 ,呈特征性排列和嗜酸性粒细胞浸润为其组织学特征 ,免疫组化结果显示病变组织表达纤维和肌纤维母细胞标记。本组均经手术切除或内镜下摘除。 11例获随访 ,其中 2例出现复发 ,均予再次手术切除 ;其余病例均恢复满意。 结论 IFP是胃肠道少见的良性病变 ,可能是对感染、异物或损伤等的过度反应 ;病理上有特征性组织学改变 ,应注意与胃肠道肿瘤或其它息肉样病变的鉴别 ;手术切除或内镜下摘除为其主要治疗方法。
Objective To investigate the diagnosis, pathological features and treatment principles of inflammatory fibrous polyposis (IFP) in the gastrointestinal tract. Methods The clinical and pathological data of 12 cases of IFP treated from 1984 to 1999 were analyzed and summarized. RESULTS: All of the 12 patients showed polypoid masses in the gastrointestinal tract. The fibrovascular hyperplasia was characterized by characteristic arrangement and infiltration of eosinophils. The results of immunohistochemistry showed that the lesions expressed fibroblasts and myofibroblasts. . The group was surgically removed or endoscopically removed. 11 cases were followed up, of which 2 cases had recurrences and all were re-surgically removed; the remaining cases were all satisfactory. Conclusions IFP is a benign lesion rarely seen in the gastrointestinal tract. It may be an overreaction to infections, foreign bodies, or injuries. It has characteristic histological changes in pathology and should be distinguished from gastrointestinal tumors or other polypoid lesions; surgical resection Or endoscopic removal is its main treatment.