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目的研究多种微量元素联合兰菌净预防老年人呼吸道感染效果,以期为老年人预防呼吸道感染提供参考依据。方法选取于2003年1月-2010年3月进行健康体检人员98名,年龄52~71岁、平均(61±4.2)岁,随机分为研究组51名和对照组47名,研究组给予兰菌净舌下滴入联合微量元素口服,对照组单纯给予多种微量元素口服用药,比较两组老年人用药前后免疫球蛋白(IgA、IgG、IgM)含量变化及用药后1年内发生呼吸道感染次数,数据采用SPSS17.0进行统计分析。结果用药前两组老年人免疫球蛋白水平差异无统计学意义,用药后两个月研究组IgA、IgG含量均高于对照组,差异有统计学意义(P<0.05),两组IgM指标差异无统计学意义;对两组老年人进行随访,1年内51名研究组发生1、2次及≥3次呼吸道感染发生率分别为21.57%、9.80%及1.96%,明显低于对照组的40.43%、12.77%及10.64%,差异有统计学意义(P<0.05)。结论多种微量元素联合兰菌净能有效预防与减少老年人呼吸道感染次数,免疫球蛋白均有所增加。
Objective To study the effect of multiple trace elements combined with Lactobacillus in the prevention of respiratory tract infections in the elderly in order to provide a reference for the prevention of respiratory tract infections in the elderly. Methods From January 2003 to March 2010, 98 healthy physical examiners (aged 52-71 years, average 61 ± 4.2 years) were randomly divided into study group 51 and control group 47. The study group was given LanBiao The patients in the control group were given oral administration of various trace elements alone. The changes of immunoglobulin (IgA, IgG, IgM) contents before and after treatment were compared with the number of respiratory tract infections within one year after treatment. Data using SPSS17.0 statistical analysis. Results There was no significant difference in immunoglobulin levels between the two groups before treatment. The levels of IgA and IgG in study group two months after treatment were significantly higher than those in control group (P <0.05) There was no significant difference between the two groups. The incidence rates of 1, 2 and 3 respiratory infections in 51 study groups in one year were 21.57%, 9.80% and 1.96%, respectively, which were significantly lower than those in control group %, 12.77% and 10.64%, respectively, the difference was statistically significant (P <0.05). Conclusion A combination of trace elements and lancaster net can effectively prevent and reduce the number of respiratory infections in elderly patients, immunoglobulin increased.