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调查本地区妊娠妇女ＴＯＲＣＨ感染的发生率以及母婴垂直传播发生情况，从而指导优生优育。方法：采用ＥＬＩＳＡ法，对我院８８２例孕中期或晚期孕妇外周血血清和相应产妇脐血血清行ＴＯＲＣＨ系列抗体（ＩｇＧ、ＩｇＭ）筛查。结果：ＴＯＲＣＨ系列特异性抗体阳性１９５例，阳性率为２２．１％；其中单项病毒抗体阳性９３例，双项阳性５５例，三项阳性３７例，四项阳性者１０例；ＴＯＲＣＨ系列ＩｇＧ阳性１０７例，ＩｇＭ阳性１２８例，ＩｇＧ、ＩｇＭ均阳性１０９例。脐血特异性抗体ＩｇＧ阳性１１６例，ＩｇＭ阳性１１例，其垂直传播率ＣＭＶ５０％、ＲＵＶ２４．７％、ＴＯＸ３１．８％、ＨＳＶ２３３．３％。感染组与未感染组比较对胎婴儿影响极大，特别是胎儿生长发育、围产儿死亡以及对ＩｇＭ阳性病例复采用ＰＣＲ测定法，进一步确诊。对ＴＯＲＣＨ阳性患者应采取相应措施
To investigate the incidence of TORCH infection in pregnant women in the region and the incidence of vertical transmission of mother and baby to guide prenatal and postnatal care. Methods: TORCH antibodies (IgG, IgM) were detected in 882 pregnant women in the second or third trimester of pregnant women with cord blood serum by ELISA. Results: TORCH series of specific antibodies were positive in 195 cases, the positive rate was 22.1%. Among them, 93 cases were single antibody positive, 55 cases were double positive, 37 cases were positive, 10 cases were positive and 10 cases were positive. TORCH IgG 107 cases, IgM positive in 128 cases, IgG, IgM were 109 cases of positive. 116 cases of umbilical cord blood specific IgG were positive and 11 cases were IgM positive. The vertical transmission rate was 50% of CMV, 24.7% of RUV, 31.8% of TOX and 233.3% of HSV. Compared with uninfected group, the infected group had a great impact on fetus, especially fetus growth, perinatal death and PCR assay for IgM-positive cases, further confirmed. TORCH-positive patients should take appropriate measures