In vitro biological screening of the stem of Desmodium elegans

• 作 者: Arshad Khan Rabia Usman Ming-Liang Wang Abdur Rauf Naveed Muhammad Akhatar Aman Taha Hussein Musa Tahir
• 机 构: School of Chemistry and Chemical Engineering Southeast University,Institute of Chemical Sciences,Uni
• 出 处: Asian Pacific Journal of Tropical Biomedicine
• 发表日期: 2013年09期
• 关键词: screening insecticidal antibacterial cytotoxic antifungal acetate shrimp hexane

Objective:To explore the medicinal importance of the stem of Desmodium elegans,methanolic extract,and its different solvent fractions were evaluated for brine shrimp lethality,insecticidal and phytotoxicity,antifungal,and antibacterial activities.Methods:The methanolic extract and its solvent fractions were tested for cytotoxic,phytotoxic,insecticidal,antifungal,and antibacterial effects using our previous published protocols.Results:The methanolic,DCM,ethyl acetate and n-butanol fractions exhibited insecticidal effect against Callosobruchus analis and Rhyzopertha dominie.The methanolic extract,n-hexane,DCM ethyl acetate and n-butanol showed 75,85,85,65 and 5%phytotoxicity at the tested concentration of 500μg/ml.respectively.The solvent fractions(DCM and ethyl acetate)were effective against F.solani(10%and 20%,inhibition respectively).All the tested samples were devoid of cytotoxic and antibacterial effects.Conclusions:It was concluded diat diis plant can be practiced for control of weeds and insects.

Objective: To explore the medicinal importance of the stem of Desmodium elegans, methanolic extract, and its different solvent fractions were evaluated for brine shrimp lethality, insecticidal and phytotoxicity, antifungal, and antibacterial activities. Methods: The methanolic extract and its solvent fractions were tested. for cytotoxic, phytotoxic, insecticidal, antifungal, and antibacterial effects using our previous published protocols. Results: The methanolic, DCM, ethyl acetate and n-butanol fractions extracted insecticidal effect against Callosobruchus analis and Rhyzopertha dominie. methanolic extract, n-hexane, DCM ethyl acetate and n-butanol showed 75,85,85,65 and 5% phytotoxicity at the tested concentration of 500 μg / ml. Specifically, the solvent fractions (DCM and ethyl acetate) were effective against F. solani (10% and 20 %, inhibition respectively). All the tested samples were devoid of cytotoxic and antibacterial effects. Conclusions: It was concluded diat diis plant can be practiced for control of w eeds and insects.