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目的探讨儿童过敏性紫癜(HSP)并神经系统损害的发病情况及临床表现。方法回顾性分析2004年1月—2010年1月收住我科的23例HSP并神经系统损害患儿的临床资料,对其发生率、临床表现与其他系统损害的关系和预后,结合随访进行分析。结果并神经系统损害的23例均为多个系统受累,其中头痛9例,嗜睡2例,抽搐3例,精神行为异常8例,抽搐昏迷死亡1例。23例中22例预后良好,1例死亡。结论 HSP患儿神经系统表现无特异性,某些患儿病情凶险危及生命,应引起临床足够重视,早期认识并及时处理非常重要。
Objective To investigate the incidence and clinical manifestations of Henoch-Schonlein purpura (HSP) in children with nervous system damage. Methods The clinical data of 23 children with HSP and neurological impairment who were admitted to our department from January 2004 to January 2010 were analyzed retrospectively. The incidence and clinical manifestations were compared with those of other systemic injuries and follow-up analysis. The results and nervous system damage were 23 cases of multiple system involvement, including headache in 9 cases, drowsiness in 2 cases, convulsions in 3 cases, 8 cases of mental disorders, convulsions and coma death in 1 case. Among the 23 cases, 22 had a good prognosis and 1 died. Conclusion There is no specific manifestation of nervous system in children with HSP. Some children are dangerous and endangering their life. It is important to pay enough attention to the disease in clinic and to recognize and deal with it in time.