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目的探讨解剖性肝切除联合脾切除对肝癌合并门脉高压并脾亢患者的治疗价值,以期为临床诊疗工作提供理论支持。方法选取64例确诊为肝癌合并门脉高压并脾亢的患者,依随机的原则分为二组,观察组共32例,应用解剖性肝切除联合脾切除进行治疗,对照组共32例,应用传统的手术方法,观察相关临床特征的改变。结果二组患者均顺利完成手术,对血细胞症及肝功能的改善均明显,但观察组术后并发症的发生率明显低于对照组,观察组术后3年生存率明显高于对照组。结论解剖性肝切除联合脾切除对肝癌合并门脉高压并脾亢患者的疗效明显,并可以提高术后患者的生存率,临床治疗中可以应用。
Objective To investigate the value of anatomical liver resection combined with splenectomy in the treatment of hepatocellular carcinoma with portal hypertension and hypersplenism, in order to provide theoretical support for clinical diagnosis and treatment. Methods Sixty-four patients with hepatocellular carcinoma complicated with portal hypertension and hypersplenism were selected and divided into two groups according to the principle of randomization. The observation group consisted of 32 cases, which were treated by anatomic hepatectomy combined with splenectomy. The control group consisted of 32 cases. Traditional surgical methods to observe changes in clinical features. Results The patients in both groups were successfully completed the operation, the improvement of hemocytosis and liver function were obvious, but the incidence of postoperative complications in the observation group was significantly lower than that in the control group. The 3-year survival rate in the observation group was significantly higher than that in the control group. Conclusions Anatomic liver resection combined with splenectomy has obvious curative effect on patients with hepatocellular carcinoma complicated with portal hypertension and hypersplenism, and can improve the survival rate of patients after operation, which can be applied in clinical treatment.