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目的头孢曲松钠与左氧氟沙星治疗老年社区获得性肺炎(CAP)的临床疗效和不良反应。方法将50例CAP患者,随机分为两组,治疗组为头孢曲松钠与左氧氟沙星组(n=25),对照组为单纯用头孢曲松钠(n=25),疗程均为7~14d,观察两组患者的临床治疗效果和不良反应发生情况。结果治疗组和对照组患者治疗总有效率分别为96.00%和84.00%,两组差异有统计学意义(P<0.05)。治疗组和对照组患者不良反应发生率分别为12.50%和8.33%,两组差异无统计学意义(P>0.05)。结论头孢曲松钠与左氧氟沙星治疗老年社区获得性肺炎,可提高疗效,缩短病程,耐受性良好。
Objective To investigate the clinical efficacy and adverse reactions of ceftriaxone sodium and levofloxacin in the treatment of elderly community-acquired pneumonia (CAP). Methods Fifty CAP patients were randomly divided into two groups. The treatment group was ceftriaxone sodium and levofloxacin group (n = 25), while the control group was ceftriaxone sodium alone (n = 25). The course of treatment was 7-14 days The clinical effects and adverse reactions of two groups were observed. Results The total effective rates of the treatment group and the control group were 96.00% and 84.00%, respectively, with significant difference between the two groups (P <0.05). Adverse reactions in treatment group and control group were 12.50% and 8.33% respectively, with no significant difference between the two groups (P> 0.05). Conclusion Ceftriaxone sodium and levofloxacin treatment of elderly community-acquired pneumonia, can improve the curative effect, shorten the course of disease, well tolerated.