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同时采用胃窦面积和胃底-体交界前后壁内径实时超声显像法对13例功能性消化不良(FD)和10例健康志愿者对照。观察比较两组的胃液体排空功能,并判断西沙必利的促动效果。结果显示:FD组与对照组比较,除胃底-胃体交界前后壁内径50%胃排空时间外,两种方法的胃50%、80%和100%胃排空时间均明显延长(p<0.01)投予西沙必利10mg后,FD组的胃排空时间明显缩短(p<0.01),健康对照组服药前后无显著差异性(p>0.05),测量胃窦面积与胃底-体前后壁内径两种方法结果无显著差异性(p>0.05)。提示:胃实时超声是研究胃动力学的一种简便、准确又无放射性的方法。西沙必利对FD患者具有显著的胃促动、加速胃液体排空的作用。
Thirteen patients with functional dyspepsia (FD) and 10 healthy volunteers were enrolled in this study by real-time ultrasound imaging of antrum area and anterior and posterior wall of the fundus-body junction. The gastric emptying function was observed and compared between the two groups, and the motivation of cisapride was evaluated. The results showed that 50%, 80% and 100% gastric emptying time of the two methods were significantly prolonged except for the gastric emptying time of 50% of the anterior and posterior wall of the stomach in the FD group compared with the control group (p <0.01), the time of gastric emptying in FD group was significantly shorter (p <0.01) after administration of cisapride 10 mg, there was no significant difference (P> 0.05) before and after administration of cisapride in gastric antrum There was no significant difference between the two methods (P> 0.05). Tip: Gastric real-time ultrasound is a simple, accurate and non-radioactive method of studying gastric dynamics. Cisapride has a significant gastric motility in FD patients and accelerates gastric emptying.