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对该组病变的主要组织学类型及其增殖细胞核抗原（ＰＣＮＡ）的表达进行了研究。本组病例，胆固醇息肉发生率占５９．４％，腺瘤占２１．９％，炎性息肉占９．４％，腺癌占９．４％。２２例息肉的ＰＣＮＡ免疫组化染色均为阴性，３例腺癌均呈ＰＣＮＡ核阳性染色反应，７例腺瘤中，１例瘤组织中出现上皮灶性不典型增生改变，其核呈阳性染色，其余６例均呈ＰＣＮＡ核阴性反应。结果提示：此类腺瘤有潜在恶性可能；ＰＣＮＡ表达可以作为腺瘤恶变及腺癌辅助诊断指标。
The main histological types and the expression of proliferating cell nuclear antigen (PCNA) in this group of lesions were studied. This group of patients, the incidence of cholesterol polyps accounted for 59.4%, 21.9% of adenomas, inflammatory polyps 9.4%, adenocarcinoma accounted for 9.4%. The PCNA immunohistochemical staining of 22 cases of polyps was negative, and all three cases of adenocarcinoma showed positive staining of PCNA. In 7 cases of adenoma, epithelial focal dysplasia appeared in 1 case of tumor and the nucleus was positive , The remaining 6 cases were PCNA nuclear negative reaction. The results suggest that: this kind of adenoma has potential malignancy; PCNA expression can be used as adenoma malignant and auxiliary diagnosis of adenocarcinoma.