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O’Connor 及其同事提出,某些患者胃溃疡的发生可能与幽门弯曲菌(Campylobacter pylori,CP)引起胃粘膜损伤有关.而在 CP 阴性的患者,十二指肠-胃返流可能是一个重要的致病因素,因为这些患者的胃活验标本显示返流性胃炎的计分更高.针对某些伴有胆汁返流的病例,他们所提出的返流性胃炎的概念有一定的价值,其根据是胃内胆酸浓度增高,并结合组织病理学特征,如小凹增生而无炎性细胞浸润。但这是总结了一组含相当数量的胃部分切除患者的检查结果而提出的观点。对胃部分切除患者,除单纯的胆汁返流外,其他因素,如无胃窦粘膜所分泌的胃泌素的营养作用和胃酸分泌减少也可影响胃粘膜的
O’Connor and colleagues suggest that gastric ulcer may be associated with gastric mucosal lesions in some patients with Campylobacter pylori (CP), whereas in patients with CP negative duodenum-gastric reflux may be a An important causative agent because gastric biopsy specimens from these patients show a higher score for reflux gastritis.For some cases with biliary reflux, the concept of regurgitant gastritis they propose is of some value , Which is based on an increase in the concentration of bile acid in the stomach combined with histopathological features, such as the proliferation of small recesses without inflammatory cell infiltration. However, this is a summary of a group of patients with a considerable number of partial resection of the results of the examination made the point of view. In patients with partial gastric resection, in addition to simple bile reflux, other factors, such as the secretion of gastric gastrin secretion and gastric acid secretion and gastric acid secretion can also affect the reduction of gastric mucosa