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最近《中华劳动卫生职业病杂志》和《新特约情报》报道了二巯基丁二酸(DMSA)的应用研究动向。作者关贵民根据国内外大量资料对DMSA的药理作用、解毒效果及口服应用等问题作了系统综述。DMSA的解毒效力主要取决于它对金属离子的亲和力,其络合能力按照镉>铅>铁>汞>锌>镍的顺序逐渐减弱。临床与动物实验均证明,DMSA对体内正常存在的微量金属元素影
Recently, “Chinese Journal of Occupational Health and Occupational Diseases” and “new special intelligence” reported dimercaptosuccinic acid (DMSA) application research trends. Guan Guimin based on a large number of domestic and foreign information on the pharmacological effects of DMSA, detoxification effect and oral applications such as a systematic review. The detoxification efficacy of DMSA depends mainly on its affinity for metal ions, and its complexing ability diminishes in the order of cadmium> lead> iron> mercury> zinc> nickel. Clinical and animal experiments have proved DMSA trace of the normal presence of trace elements in the body