【摘 要】
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Dear Editor,Many forms of sight-threatening diseases,including retinitis pigmentosa (RP) and age-related macular degeneration (AMD),are caused by the dysfunctio
【机 构】
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Savaid Medical School, University of Chinese Academy of Sciences, Beijing 100049, China “,”State Key
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Dear Editor,Many forms of sight-threatening diseases,including retinitis pigmentosa (RP) and age-related macular degeneration (AMD),are caused by the dysfunction,degeneration and loss of the retinal pigment epithelium (RPE) (Strauss,2005).RPE cell transplantation may potentially recover or halt disease progression,in which human embryonic stem cells (hESCs) could serve as an unlimited donor source for RPE differentiation,and a few clinical trials have shown the safety and effective of transplantation of hESCs-derived RPE (hESC-RPE) for AMD patients (Schwartz et al.,2012;Schwartz et al.,2015;Song et al.,2015;da Cruz et al.,2018;Kashani et al.,2018;Liu et al.,2018).
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